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Ken D. Shimizu (updated 1/2024)

Professor
Department of Chemistry and Biochemistry University of South Carolina
Columbia, SC 29208

Research Interests: Supramolecular Chemistry, Molecular Recognition, Physical Organic Chemistry, Molecularly Imprinted Polymers, Materials Chemistry

Professional Experience

1997-2003 Assistant Professor, University of South Carolina

2003-2010 Associate Professor, University of South Carolina

2010-present Professor, University of South Carolina

2015-2021 Department Chair, University of South Carolina

Education

1990 B.A. (Chemistry) Cornell University

1995 Ph.D. (Chemistry) Massachusetts Institute of Technology

1995-1997 NIH Postdoctoral Fellow, Boston College

Honors and Awards:

Russell Research Award
SC ACS Chemist of the Year
SERMACS Symposium Organizer: “Supramolecular
Session Chair for Mesilla Workshop on Aromatic Interactions
Editorial Advisory Board: Molecular Imprinting
Co-organizer of 6th International Molecular Imprinting Conference
Editorial Board Organic Chemistry International
Editorial Advisory Board: Journal of Molecular Recognition
Mungo Undergraduate Teaching Award
Organized SERMACS session on Functional polymers and biomacromolecules Japan Society for the Promotion of Science (JSPS) Fellowship
Mortar Board Excellence in Teaching Award
Research Corporation Research Innovation Award
NIH Postdoctoral Fellowship
CRC Award for Achievement in Organic Chemistry

Research Highlights

Paper on “Hydrogen bond TS stabilization” highlighted in Chemistry World 2020
Cover and Hot article in Organic & Biomolecular Chemistry vol 15 2017
Paper on “Silver-pi interaction” highlighted in ChemistryViews magazine 2015
Paper on “Silver-pi interaction” highlighted in ACS Noteworthy Chemistry 2015
Paper on “Proton Grease” highlighted in RSC Chemistry World 2012
Article on cover of Current Opinion in Chemical Biology vol 14 2010 Interviewed and quoted in Technology Review magazine (June) 2010
Paper (Org. Lett., 2009, 11, 2599) highlighted in ACS Noteworthy column Aug 2009
Paper (J. Am. Chem. Soc., 2009, 131, 12062) highlighted in Chem. & Eng. News, 87(35) 2009 Paper (Org. Lett., 2008, 10, 3547) highlighted in Nature Chem. Aug. 1 2008 Interviewed and quoted in Technology Review magazine (Oct.) 2008

Paper (Chem. Comm, 2007, 3, 228) highlighted in MRS Bulletin, 32, 302 2007 Paper (Chem. Comm. 2004, 10, 1172) among 10 most downloaded articles 2004 Paper (Chem. Comm. 2004, 10, 1172) highlighted in ACS Heartcut, June 2004 ACS meeting presentation highlighted in Chem. & Eng. News, 80(23), 51 2002 Presentation highlighted in MRS Bulletin, 27, 563 2002 Cover article of Analyst vol 125 2000

Synergistic Activities

  • Research Advisor for 23 Ph.D. students
  • Research Advisor for 7 M.S. students
  • Research Advisor for 10 high school students in research activities
  • Research Advisor for 37 undergraduate students
  • NSF CHE review panel (2024)
  • NSF CHE review panel (2023)
  • NSF LEAPS review panel (2022)
  • NSF CHE review panel (2020)
  • NSF CCI review panel (2016)
  • NSF CBET review panel (2015)
  • Deutsche Forschungsgemeinschaft (DFG) review panel (2014)
  • NSF MSN review panel (2014)
  • NSF MSN review panel (2011)
  • NSF CBET review panel (2011)
  • NSF CBET review panel (2008)
  • NSF CBET review panel (2007)
  • NSF SBIR review panel (2007)
  • NIH SBCA study section 2006
  • NIH BCMBIRG study section (2006)
  • Faculty mentor for High School lab experience SCienceLab (2008 – 2012)
  • Mentor / research director for 5 Undergraduates in NSF Research Experiences for Undergraduates (REU) Program in Nanoscience.
  • Mentor / thesis advisor for the University of South Carolina Honors College.
  • Faculty advisor for local South Carolina American Chemical Society Chapter (SACS)Research funding (PI awards)
  • NSF, “Development of Molecular Devices for the Study of Emerging Non-Covalent Interactions” PI, $491,394, 11/01/2023 – 10/31/2026
  • PRF, “Hydrogen Bonding Protecting Groups” PI, $110,000, 01/01/2023 – 12/31/2024.
  • NSF, “Molecular rotors for studying transition state stabilization by non-covalent interactions”PI, $447,500, 08/01/2020 – 07/31/2023
  • NSF MRI Q-Exactive MS co-PI $450,000, 09/2018 – 08/2019
  • EPSCoR, “Collaborative Research Program (CRP): Programmable Polymers Based on Restricted Rotation Formed by Free Radical Polymerization” $60,000, 05/2018 to 04/2019
  • NSF, “Comprehensive Models of Non-Covalent Aromatic Interactions” $460,000, 8/2017 to 07/2020
  • NSF, “Molecular balance for measuring molecular-level anion effects on amino acids” $390,000, 9/2013 to 09/2016
  • EPSCoR, “Collaborative Research Program (CRP): Colorimetric molecular sensors for monitoring stress and strain in synthetic blood vessels” $100,000, 01/2013 to 06/2014
  • NSF, “Programmable polymers based on restricted rotation” $390,000, 10/01/2011 to 09/30/2014
  • NSF, “US Egypt Cooperative Research: Luminescent Molecularly Imprinted Polymer Sensor Arrays” PI, $125,000, 8/01/2011 to 7/31/2014
  • NSF, “A molecular balance for studying the non-covalent interactions of aromatic surfaces” PI, $460,000, 8/01/2009 to 7/31/2013.
  • NSF, “New Strategies for Improved Molecularly Imprinted Polymers”, $250,000, 8/15/08 to 8/14/11
  • NIH, “New Strategies for Improved Imprinted Polymers”, $1,128,906, 3/01-3/07
  • PRF, “New Model Systems to Measure Weak Non-covalent Interactions”, $90,000, 09/01/07to 08/3/09
  • NSF, “Conformationally Programmable Molecular Receptors”, $420,000, 08/06 to 06/09
  • NSF, “Conformationally Programmable Molecular Receptors”, $399,000, 07/15/03 to 07/14/06
  • NSF, “Synthetic Self-Assembling Polyimides”, $370,002, 9/01/98 – 8/31/03. Publications (105 total; H-index: 47 Google Scholar, 41 Web of Science )
  1. N. Manzewitsch, H. Liu, B. Lin, P. Li, P. J. Pellechia and K. D. Shimizu, Empirical Model of Solvophobic Interactions in Organic Solvents, Angew Chem Int Ed, 2024, 63, e202314962.
  2. H. Liu and K. D. Shimizu, Contributions of London Dispersion Forces to Solution-Phase Association Processes, Acc. Chem. Res., 2023, 56, 3572–3580.
  3. B. Lin, H. Liu, I. Karki, E. C. Vik, M. D. Smith, P. J. Pellechia and K. D. Shimizu, Pnictogen Interactions with Nitrogen Acceptors, Angew Chem Int Ed, 2023, e202304960.
  4. B. Lin, I. Karki, P. J. Pellechia and K. D. Shimizu, “Electrostatically-gated molecular rotors”, Chem. Commun., 2022, 58, 5869–5872.
  5. E. C. Vik, P. Li, D. O. Madukwe, I. Karki, G. S. Tibbetts, K. D. Shimizu, “Analysis of the Orbital and Electrostatic Contributions to the Lone Pair–Aromatic Interaction Using Molecular Rotors”, Org. Lett., 2021, 23, 8179–8182.
  6. Karki, P. Li, E.C. Vik, A. Manzewitsch, E. Divirgilio, W.E. Brewer, K.D. Shimizu, “Absorption properties of monolithic poly (divinylbenzene-co-N-vinylpyrrolidone) over a wide range of monomer ratios”, Reactive and Functional Polymers. 2021, 163, 104888.
  7. P. Li, E. C.Vik, K. D. Shimizu, “N -Arylimide Molecular Balances: A Comprehensive Platform for Studying Aromatic Interactions in Solution.” Acc. Chem. Res. 2020, 53, 2705–2714.
  8. E.C. Vik, P. Li, J.M. Maier, D.O. Madukwe, V.A. Rassolov, P.J. Pellechia, E. Masson, K.D. Shimizu, “Large transition state stabilization from a weak hydrogen bond”, Chem. Sci. 2020, 11, 7487–7494.
  9. E.C. Vik, P. Li, P.J. Pellechia, K.D. Shimizu, “Transition-State Stabilization by n→π* Interactions Measured Using Molecular Rotors”, J. Am. Chem. Soc. 2019, 141, 16579–16583
  10. P. Li, E. C. Vik, J. M. Maier, I. Karki, S. M. S. Strickland, J. M. Umana, M. D. Smith, P. J. Pellechia and K. D. Shimizu, “”, J. Am. Chem. Soc., 2019, 141, 12513–12517.
  11. J. Hwang, P. Li, E. C. Vik, I. Karki, K. D. Shimizu, “Study of Through-Space Substituent–π interactions using N-Phenylimide Molecular Balances.” Org. Chem. Front. 2019, 6, 1266-1271.
  12. J. M. Maier, P. Li, J. S. Ritchey, C. J. Yehl, K. D. Shimizu, “Anion-enhanced solvophobic effects in organic solvent.” Chem. Commun. 2018, 54, 8502–8505.
  13. J. Hwang, P. Li, M. D. Smith, C. E. Warden, D. A. Sirianni, E. C. Vik, J. M. Maier, C. J. Yehl, C. D. Sherrill, K. D. Shimizu, “Tipping the Balance between S-π and O-π Interactions”. J. Am. Chem. Soc. 2018, 140 (41), 13301-13307.
  14. L. Ping, W. J. Richardson, D. Song and K. D. Shimizu, “Chapter 14: Molecularly Imprinted Polymer Sensor Arrays” in Molecularly Imprinted Polymers for Analytical Chemistry Applications:, ed. W. Kutner, Royal Society of Chemistry, Cambridge, 2018.
  15. J. M. Maier, P. Li, E. C. Vik, C. J. Yehl, S. M. S. Strickland and K. D. Shimizu, “Measurement of Solvent OH−π Interactions Using a Molecular Balance”, J. Am. Chem. Soc., 2017, 139, 6550– 6553.
  16. P. Li, J. M. Maier, E. C. Vik, C. J. Yehl, B. E. Dial, A. E. Rickher, M. D. Smith, P. J. Pellechia and K. D. Shimizu, “Stabilizing Fluorine-π Interactions”, Angew. Chem., Int. Ed., 2017, 56, 7209– 7212.
  17. G. Rushton, E. C. Vik, W. G. Burns, R. D. Rasberry and K. D. Shimizu, “Guest control of a hydrogen bond-catalysed molecular rotor”, Chem. Commun., 2017, 53, 12469–12472.
  18. J Hwang, P. Li, K. D. Shimizu. “Synergy between experimental and computational studies of aromatic stacking interactions.” Org. Biomol. Chem. 2017, 15, 1554–1564. (Cover Article and 2017 Hot Article in Organic and Biomolecular Chemistry)
  19. K. D. Shimizu, P. Li, J Hwang. “CHAPTER 5. Solution-Phase Measurements of Aromatic Interactions.” in Monographs in Supramolecular Chemistry (eds. Johnson, D. W. & Hof, F.) (Royal Society of Chemistry) 2016, 124–171.
  1. P. Li; J. M. Maier; J. Hwang; M. D. Smith; J. A. Krause; B. T. Mullis; S. M. S. Strickland; K. D. Shimizu. “Solvent-induced reversible solid-state colour change of an intramolecular charge- transfer complex” Chem. Commun., 2015, 51, 14809-14812.
  2. J. M. Maier; P. Li; J. Hwang; M. D. Smith; K. D. Shimizu. “Measurement of Silver-pi Interactions in Solution Using Molecular Torsion Balances” J. Am. Chem. Soc., 2015, 137, 8014-8017.
  3. J. Hwang; B. E. Dial; P. Li; M. E. Kozik; M. D. Smith; K. Shimizu. “How important are dispersion interactions to the strength of aromatic stacking interactions in solution?” Chemical Science, 2015, 6, 4358-4364.
  4. P. Li; J. Hwang; J. M. Maier; C. Zhao; D. V. Kaborda; M. D. Smith; P. J. Pellechia; K. D. Shimizu. “Correlation between Solid-State and Solution Conformational Ratios in a Series of N-(o- Tolyl)Succinimide Molecular Rotors.” Cryst. Growth Des. Crystal Growth & Design, 2015, 15, 3561-3564.
  5. P. Li, T. M. Parker, J. Hwang, F. Deng, M. D. Smith, P. J. Pellechia, C. D. Sherrill, K. D. Shimizu. “The CH-pi Interactions of Methyl Ethers as a Model for Carbohydrate-N-Heteroarene Interactions.” Org. Lett., 2014, 5064-5067.
  6. M. J. Maher, K. Yehl, F. Haque, A. Faint, K. D. Shimizu, C. J. Stephenson. “Surprising variations in the rate of ring opening for a series of rhodamine lactams with similar equilibrium endpoints.” Sens. Actuators, B Sensors and Actuators, B: Chemical, 2014, 200, 1-8.
  7. C. Zhao, P. Li, M. D. Smith, P. J. Pellechia, K. D. Shimizu. “Experimental Study of the Cooperativity of CH-pi Interactions.” Org. Lett., 2014, 16, 3520-3523.
  8. D. Song, Y. Zhang, M. F. Geer, K. D. Shimizu. “Characterization of molecularly imprinted polymers using a new polar solvent titration method.” J. Mol. Recognit., 2014, 27, 448-457.
  9. J. Hwang, P. Li, W. R. Carroll, P. J. Pellechia, K. D. Shimizu. “Additivity of substituent effects in aromatic stacking interactions.” J. Am. Chem. Soc., 2014, 136, 14060–14067
  10. K. D. Shimizu. “Intermolecular forces: A solution to dispersion interactions.” Nat Chem, 2013, 5, 989-990. (Invited commentary)
  11. P. Li, C. Zhao, M. D. Smith, K. D. Shimizu. “Comprehensive Experimental Study of N- Heterocyclic pi-Stacking Interactions of Neutral and Cationic Pyridines.” J. Org. Chem., 2013, 78, 5303-5313.
  12. B. E. Dial, P. J. Pellechia, M. D. Smith, K. D. Shimizu. “Proton Grease: An Acid Accelerated Molecular Rotor” J. Am. Chem. Soc., 2012, 134, 3675-3678.
  13. R. D. Rasberry, K. D. Shimizu. “Molecular Machines” in eds. J. L. Atwood, J. W. Steed, Taylor & Francis, 2012, Encyclopedia of Supramolecular Chemistry
  14. C. Zhao, R. M. Parrish, M. D. Smith, P. J. Pellechia, C. D. Sherrill, K. D. Shimizu. “Do Deuteriums Form Stronger CH-pi Interactions?” J. Am. Chem. Soc., 2012, 134, 14306-14309.
  15. L. X. Ren, J. Y. Zhang, X. L. Bai, C. G. Hardy, K. D. Shimizu, C. B. Tang. “Preparation of cationic cobaltocenium polymers and block copolymers by “living” ring-opening metathesis polymerization” Chem Sci, 2012, 3, 580-583.
  16. Y. S. Chong, B. E. Dial, W. G. Burns, K. D. Shimizu. “Covalent locking and unlocking of an atropisomeric molecular switch” Chem. Commun., 2012, 48, 1296-1298.
  1. Y. Zhang, K. D. Shimizu. “Molecular imprinting and sensor development” in Chemosensors: Principles, Strategies, and Applications, eds. B. Wang, E. V. Anslyn, John Wiley & Sons, Hoboken, NewJersey, 2011, pp. 107-120.
  2. W. R. Carroll, C. Zhao, M. D. Smith, P. J. Pellechia, K. D. Shimizu. “A Molecular Balance for Measuring Aliphatic CH-pi Interactions.” Org. Lett., 2011, 13, 4320-4323.
  3. B. E. Dial, R. D. Rasberry, B. N. Bullock, M. D. Smith, P. J. Pellechia, S. Profeta, K. D. Shimizu. “Guest-Accelerated Molecular Rotor.” Org. Lett., 2011, 13, 244-247.
  4. Y. G. Zhang, D. Song, J. C. Brown, K. D. Shimizu. “Suppression of background sites in molecularly imprinted polymers via urea-urea monomer aggregation” Org. Biomol. Chem., 2011, 9, 120-126.
  5. R. D. Rasberry, K. D. Shimizu. “Molecular Machines” in eds. Taylor & Francis, 2010, Encyclopedia of Supramolecular Chemistry,
  6. K. D. Shimizu, C. J. Stephenson. “Molecularly imprinted polymer sensor arrays” Curr. Opin. Chem. Biol., 2010, 14, 743-750. (Cover Article)
  7. Y. Zhang, D. Song, L. M. Lanni, K. D. Shimizu. “Importance of Functional Monomer Dimerization in the Molecular Imprinting Process.” Macromolecules, 2010, 43, 6284-6294.
  8. K. D. Shimizu. “Reading polymer codes.” Nat. Chem., 2010, 2, 612-613. (Invited commentary)
  9. C. J. Stephenson, K. D. Shimizu. “A fluorescent diastereoselective molecular sensor for 1,2- aminoalcohols based on the rhodamine B lactone-zwitterion equilibrium” Org. Biomol. Chem., 2010, 8, 1027-1032.
  10. L. M. Hyman, C. J. Stephenson, M. G. Dickens, K. D. Shimizu, K. J. Franz. “Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress” Dalton Trans., 2010, 39, 568-576.
  11. Y. S. Chong, W. R. Carroll, W. G. Burns, M. D. Smith, K. D. Shimizu. “A High-Barrier Molecular Balance for Studying Face-to-Face Arene-Arene Interactions in the Solid State and in Solution” Chem. Eur. J., 2009, 15, 9117-9126.
  12. R. D. Rasberry, K. D. Shimizu. “Molecular playdough: conformationally programmable molecular receptors based on restricted rotation” Org. Biomol. Chem., 2009, 7, 3899-3905.
  13. Y. Zhang, J. M. Lavin, K. D. Shimizu. “Solvent Programmable Polymers Based on Restricted Rotation” J. Am. Chem. Soc., 2009, 131, 12062-12063. (Highlighted in Chem. & Eng. News, 2009, 87(35), 25-26.)
  14. R. D. Rasberry, X. Wu, B. N. Bullock, M. D. Smith, K. D. Shimizu. “A small molecule diacid with long-term chiral memory.” Org. Lett., 2009, 11, 2599-2602. (Highlighted in ACS noteworthy column Aug 31, 2009)
  15. X. Wu, K. D. Shimizu. “Development of molecularly imprinted polymers as tailored templates for the solid-state [2+2] photodimerization” Biosensors and Bioelectronics, 2009, 25, 640-646.
  16. X. G. Wu, K. Goswami, K. D. Shimizu. “Comparison of monofunctional and multifunctional monomers in phosphate binding molecularly imprinted polymers” J. Mol. Recognit., 2008, 21, 410-418.
  1. X. Wu, K. D. Shimizu. “Chapter 15. Molecular imprinting for sensor applications.” in eds. V. M. Rotello, S. Thayumanavan, John Wiley & Sons, Hoboken, NJ, 2008, Molecular Recognition and Polymers, pp. 395-429.
  2. W. R. Carroll, P. Pellechia, K. D. Shimizu. “A Rigid Molecular Balance for Measuring Face-to- Face Arene−Arene Interactions” Org. Lett., 2008, 10, 3547-3550. (Highlighted in Nature Chem. 2008, Aug)
  3. X. Y. Wu, W. R. Carroll, K. D. Shimizu. “Stochastic lattice model Simulations of molecularly imprinted polymers” Chem. Mater., 2008, 20, 4335-4346.
  4. R. D. Rasberry, M. D. Smith, K. D. Shimizu. “Origins of selectivity in a colorimetric charge-transfer sensor for diols” Org. Lett., 2008, 10, 2889-2892.
  5. G. T. Rushton, W. G. Burns, J. M. Lavin, Y. S. Chong, P. Pellechia, K. D. Shimizu. “Determination of the rotational barrier for kinetically stable conformational isomers via NMR and 2D TLC – An introductory organic chemistry experiment” J. Chem. Educ., 2007, 84, 1499-1501.
  6. C. J. Stephenson, K. D. Shimizu. “Colorimetric and fluorometric molecularly imprinted polymer sensors and binding assays” Polym. Int., 2007, 56, 482-488.
  7. J. M. Lavin, K. D. Shimizu. “A supramolecular switch with molecular memory” Chem. Commun., 2007, 228-230. (highlighted in MRS Bulletin, 2007, 32, 302)
  8. J. M. Lavin, K. D. Shimizu. “Rapid screening of a receptor with molecular memory.” Org. Lett., 2006, 2389-2392.
  9. K. D. Shimizu. “Binding Isotherms” in eds. M. Yan, O. Ramstrom, Marcel Dekker, New York, N. Y., 2005, Molecularly Imprinted Materials, pp. 419-434.
  10. J. D. Lee, N. T. Greene, G. T. Rushton, K. D. Shimizu, J. I. Hong. “Carbohydrate recognition by porphyrin-based molecularly imprinted polymers.” Org. Lett., 2005, 7, 963-966.
  11. G. T. Rushton, B. Furmanski, K. D. Shimizu. “Plastic Antibodies: Molecular Recognition with Imprinted Polymers. An Introductory Polymer Chemistry Laboratory Investigation” J. Chem. Educ., 2005, 82, 1374.
  12. C. F. Degenhardt, J. M. Lavin, M. D. Smith, K. D. Shimizu. “Conformationally imprinted receptors: atropisomers with “write”, “save”, and “erase” recognition properties.” Org. Lett., 2005, 7, 4079- 4081.
  13. K. D. Shimizu. “Post Modification of Imprinted Sites” in eds. M. Yan, O. Ramstrom, Marcel Deker, New York, N. Y., 2005, Molecularly Imprinted Materials: Science and Technology, pp. 329-345.
  14. G. T. Rushton, C. L. Karns, K. D. Shimizu. “A critical examination of the use of the Freundlich isotherm in characterizing molecularly imprinted polymers (MLPs)” Anal. Chim. Acta, 2005, 528, 107-113.
  15. G. T. Rushton, K. D. Shimizu. “Molecularly Imprinted Polymers” in Encyclopedia of Chemical Processing, eds. L. Sunggyu, CRC Press, 2005, pp. 1737-1746.
  16. N. T. Greene, K. D. Shimizu. “Colorimetric molecularly imprinted polymer sensor array using dye displacement.” J. Am. Chem. Soc., 2005, 127, 5695-5700.
  17. N. T. Greene, S. L. Morgan, K. D. Shimizu. “Molecularly imprinted polymer sensor arrays” Chem. Commun., 2004, 10, 1172-1173.
  1. H. L. Ricks, L. S. Shimizu, M. D. Smith, U. H. F. Bunz, K. D. Shimizu. “An N,N ‘-diaryl urea based conjugated polymer model system” Tetrahedron Lett., 2004, 45, 3229-3232.
  2. M. Rampey, R. J. Umpleby, G. T. Rushton, J. C. Iseman, R. N. Shah, K. D. Shimizu. “Characterization of the imprint effect and the influence of imprinting conditions on affinity, capacity, and heterogeneity in molecularly imprinted polymers using the Freundlich isotherm- affinity distribution analysis” Anal. Chem., 2004, 76, 1123-1133.
  3. D. L. Reger, D. M. C. Smith, K. D. Shimizu, M. D. Smith. “Syntheses and solid state structures of europium and terbium complexes of N,N’-bis(2-pyridylmethyl)urea and N,N’-bis(3- pyridylmethyl)oxalamide” Polyhedron, 2004, 23, 711-717.
  4. R. J. Umpleby, II, A. M. Rampey, S. C. Baxter, G. T. Rushton, R. N. Shah, J. C. Bradshaw, K. D. Shimizu. “Characterization of the heterogeneous binding site affinity distributions in molecularly imprinted polymers” J. Chromatogr. B, 2004, 804, 141-149.
  5. L. S. Shimizu, A. D. Hughes, M. D. Smith, M. J. Davis, B. P. Zhang, H. C. zur Loye, K. D. Shimizu. “Self-assembled nanotubes that reversibly bind acetic acid guests” J. Am. Chem. Soc., 2003, 125, 14972-14973.
  6. Y. H. Li, C. Y. Su, A. M. Goforth, K. D. Shimizu, K. D. Gray, M. D. Smith, H. C. zur Loye. “The first ‘two-over/two-under’ (2O/2U) 2D weave structure assembled from Hg-containing 1D coordination polymer chains” Chem. Commun., 2003, 14, 1630-1631.
  7. D. L. Reger, D. M. C. Smith, K. D. Shimizu, M. D. Smith. “N,N ‘-bis(2-pyridylmethyl)oxamidato palladium(II) monohydrate chloroform hemisolvate” Acta Crystallogr., Sect. E, 2003, 59, M652- M654.
  8. S. Shotwell, H. L. Ricks, J. G. M. Morton, M. Laskoski, J. Fiscus, M. D. Smith, K. D. Shimizu, H. C. zur Loye, U. H. F. Bunz. “Trans-spanning acetylenic bispyridine ligands: synthesis and structural characterization of novel organic and organometallic pseudodehydroannulenes” J. Organomet. Chem., 2003, 671, 43-51.
  9. K. D. Shimizu. “Characterization of MIPs Using Heterogeneous Binding Models” in eds. K. J. Shea, M. Yan, M. J. Roberts, 2002, “Molecularly Imprinted Materials-Sensors and Other Devices”, MRS Symposium Proceeding(723), pp. 17-21.
  10. S. S. Walse, K. D. Shimizu, J. L. Ferry. “Surface-catalyzed transformations of aqueous endosulfan” Environ. Sci. Technol., 2002, 36, 4846-4853.
  11. Y. Chen, K. D. Shimizu. “Measurement of Enantiomeric Excess Using Molecularly Imprinted Polymers” Org. Lett., 2002, 4, 2937-2940.
  12. Y. S. Chong, K. D. Shimizu. “Shape-Persistent and Shape-Adaptable Macrocycles Based on Restricted Rotation: Studies Toward Building ‘Macromolecular Playdough’” Synthesis, 2002, 9, 1239-1244.
  13. C. F. Degenhardt, M. D. Smith, K. D. Shimizu. “A chiral 28-membered macrocycle with symmetry and structure similar to that of trans-cyclooctene” Org. Lett., 2002, 4, 723-726.
  14. D.-S. Choi, Y. S. Chong, D. Whitehead, K. D. Shimizu. “Molecules with Shape Memory Based on Restricted Rotation” Org. Lett., 2001, 3, 3757-3760.
  1. T. Takeuchi, T. Mukawa, J. Matsui, M. Higashi, K. D. Shimizu. “Molecularly imprinted polymers with metalloporphyrin-based molecular recognition sites coassembled with methacrylic acid” Anal. Chem., 2001, 73, 3869-3874.
  2. R. J. Umpleby, II, S. C. Baxter, Y. Chen, R. N. Shah, K. D. Shimizu. “Characterization of Molecularly Imprinted Polymers with the Langmuir-Freundlich Isotherm” Anal. Chem., 2001, 73, 4584-4591.
  3. L. S. Shimizu, M. D. Smith, A. D. Hughes, K. D. Shimizu. “Self-assembly of a bis-urea macrocycle into a columnar nanotube” Chem. Commun., 2001, 17, 1592-1593.
  4. M. Levitus, K. Schmieder, H. Ricks, K. D. Shimizu, U. H. F. Bunz, M. A. Garcia-Garibay. “Steps to demarcate the effects of chromophore aggregation and planarization in poly(phenyleneethynylene)s. 1. Rotationally interrupted conjugation in the excited states of 1,4- bis(phenylethynyl)benzene” J. Am. Chem. Soc., 2001, 123, 4259-4265.
  5. R. J. Umpleby, S. C. Baxter, M. Bode, J. K. Berch, R. N. Shah, K. D. Shimizu. “Application of the Freundlich adsorption isotherm in the characterization of molecularly imprinted polymers” Anal. Chim. Acta, 2001, 435, 35-42.
  6. Y. S. Chong, M. D. Smith, K. D. Shimizu. “A Conformationally Programmable Ligand” J. Am. Chem. Soc., 2001, 123, 7463-7464.
  7. Y. Z. Chen, M. D. Smith, K. D. Shimizu. “An axially chiral phosphine ligand based on restricted rotation in N-arylimides” Tetrahedron Lett., 2001, 42, 7185-7187.
  8. R. J. Umpleby, G. T. Rushton, R. N. Shah, A. M. Rampey, J. C. Bradshaw, J. K. Berch, K. D. Shimizu. “Recognition Directed Site-Selective Chemical Modification of Molecularly Imprinted Polymers” Macromolecules, 2001, 34, 8446-8452.
  9. K. D. Shimizu, H. O. Freyer, R. D. Adams. “Synthesis, resolution and structure of axially chiral atropisomeric N-arylimides” Tetrahedron Lett., 2000, 41, 5431-5434.
  10. R. J. Umpleby, II, M. Bode, K. D. Shimizu. “Measurement of the continuous distribution of binding sites in molecularly imprinted polymers” Analyst, 2000, 125, 1261-1265. (Cover Article)
  11. C. F. Degenhardt, D. B. Shortell, R. D. Adams, K. D. Shimizu. “Synthesis and structural characterization of adaptable shape-persistent building blocks” Chem. Commun., 2000, 929-930.
  12. U. H. F. Bunz, V. Enkelmann, L. Kloppenburg, D. Jones, K. D. Shimizu, J. B. Claridge, H. C. zur Loye, G. Lieser. “Solid-state structures of phenyleneethynylenes: Comparison of monomers and polymers” Chem. Mater., 1999, 11, 1416-1424.
  13. U. H. F. Bunz, G. Roidl, M. Altmann, V. Enkelmann, K. D. Shimizu. “Synthesis and structural characterization of novel organometallic dehydroannulenes with fused CpCo-cyclobutadiene and ferrocene units including a cyclic fullerenyne segment” J. Am. Chem. Soc., 1999, 121, 10719- 10726.
  14. K. D. Shimizu, M. L. Snapper, A. H. Hoveyda. “Chapter 39: Combinatorial Approaches” in eds. E. N. Jacobsen, A. Pfaltz, H. Yamamoto, Springer-Verlag, New York, 1999, Comprehensive Asymmetric Catalysis, pp.
  15. K. D. Shimizu, M. L. Snapper, A. H. Hoveyda. “High-throughput strategies for the discovery of catalysts” Chem.–Eur. J., 1998, 4, 1885-1889.

98. K. D. Shimizu, B. M. Cole, C. A. Krueger, K. W. Kuntz, M. L. Snapper, A. H. Hoveyda. “Search for chiral catalysts through ligand diversity: Substrate-specific catalysts and ligand screening on solid phase” Angew. Chem., Int. Ed. Engl., 1997, 36, 1703-1707.

99. K. D. Shimizu, J. Rebek. “A rigid trans-spanning dinitrile ligand” Proc. Natl. Acad. Sci. U. S. A., 1996, 93, 4257-4260.

100. B. C. Hamann, K. D. Shimizu, J. Rebek. “Reversible encapsulation of guest molecules calixarene dimer” Angew. Chem., Int. Ed. Engl., 1996, 35, 1326-1329.

101. B. M. Cole, K. D. Shimizu, C. A. Krueger, J. P. A. Harrity, M. L. Snapper, A. H. Hoveyda. “Discovery of chiral catalysts through ligand diversity: Ti- catalyzed enantioselective addition of TMSCN to meso epoxides” Angew. Chem., Int. Ed. Engl., 1996, 35, 1668-1671.

102. K. D. Shimizu, J. Rebek. “Synthesis and assembly of self-complementary calix[4]arenes” Proc. Natl. Acad. Sci. U. S. A., 1995, 92, 12403-12407.

103. K. D. Shimizu, T. M. Dewey, J. J. Rebek. “Convergent functional groups. 15. Synthetic and structural studies of large and rigid molecular clefts” J. Am. Chem. Soc., 1994, 116, 5145- 5149.

104. J. T. Fahey, K. Shimizu, J. M. J. Frechet, N. Clecak, C. G. Willson. “Resist System Based on the Cationic Photo-Cross-Linking of Poly(4-Hydroxystyrene) and Polyfunctional Electrophiles” J. Polym. Sci. Part. A, 1993, 31, 1-11.

105. H. Stover, S. Matuszczak, R. Chin, K. Shimizu, C. G. Willson, J. M. J. Fréchet. “Acid- Catalyzed Rearrangement of Aromatic Ethers: Model Studies and Application to Imaging.” Poly. Mat. Sci. Eng., 1989, 61, 412-416.