{"id":260,"date":"2022-07-30T16:07:25","date_gmt":"2022-07-30T16:07:25","guid":{"rendered":"https:\/\/shimizu-uofsc.net\/orgo\/?post_type=epkb_post_type_1&p=260"},"modified":"2023-09-30T18:22:08","modified_gmt":"2023-09-30T18:22:08","slug":"identify-chiral-centers","status":"publish","type":"epkb_post_type_1","link":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/knowledge-base\/identify-chiral-centers\/","title":{"rendered":"Identify Chiral Centers"},"content":{"rendered":"\n

Introduction:<\/h4>\n\n\n\n

Chiral centers are tetrahedral atoms (usually carbons) that have four different substituents.\u00a0 Each chiral center in a molecule will be either R or S.\u00a0\u00a0As noted above<\/a>, molecules with a single chiral center are chiral.\u00a0 Molecules with more than one chiral center are usually chiral.\u00a0 The exceptions are\u00a0meso-compounds<\/a>.<\/p>\n\n\n\n

How to:<\/h4>\n\n\n\n

Step 1:\u00a0<\/strong>Eliminate the atoms that cannot be chiral centers.\u00a0 These include CH2<\/sub>\u00a0groups, CH3<\/sub>\u00a0groups, oxygens, halogens, and any atom that is part of a double or triple bond.<\/p>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

Step 2: <\/strong>For the remaining atoms, list out the groups (substituents) attached to that atom.  If there are four different groups, then it is a chiral center.  (Note that two substituents can appear to be the same if you look only at the first attached atom but you have to keep going to check if they are really the same or are different.)<\/p>\n\n\n

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\"\"<\/figure>\n<\/div>","protected":false},"excerpt":{"rendered":"

Introduction: Chiral centers are tetrahedral atoms (usually carbons) that have four different substituents.\u00a0 Each chiral center in a molecule will be either R or S.\u00a0\u00a0As noted above, molecules with a single chiral center are chiral.\u00a0 Molecules with more than one chiral center are usually chiral.\u00a0 The exceptions are\u00a0meso-compounds. How to: Step 1:\u00a0Eliminate the atoms that… Read More »Identify Chiral Centers<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"nf_dc_page":"","neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"epkb_post_type_1_category":[18],"epkb_post_type_1_tag":[],"class_list":["post-260","epkb_post_type_1","type-epkb_post_type_1","status-publish","hentry","epkb_post_type_1_category-chirality-stereochemistry"],"_links":{"self":[{"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1\/260","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1"}],"about":[{"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/types\/epkb_post_type_1"}],"author":[{"embeddable":true,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/comments?post=260"}],"version-history":[{"count":2,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1\/260\/revisions"}],"predecessor-version":[{"id":457,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1\/260\/revisions\/457"}],"wp:attachment":[{"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/media?parent=260"}],"wp:term":[{"taxonomy":"epkb_post_type_1_category","embeddable":true,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1_category?post=260"},{"taxonomy":"epkb_post_type_1_tag","embeddable":true,"href":"https:\/\/shimizu-uofsc.net\/orgo\/kb\/wp-json\/wp\/v2\/epkb_post_type_1_tag?post=260"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}